Description
Product Characteristics:
Aliases: hZIMP10 antibody, KIAA1224 antibody, MIZ antibody, PIAS like protein hZimp10 antibody, PIAS like protein on chromosome 10 antibody, PIAS like protein Zimp10 antibody, PIAS-like protein Zimp10 antibody, RAI 17 antibody, Retinoic acid induced 17 antibody, Retinoic acid induced protein 17 antibody, Retinoic acid-induced protein 17 antibody, TRAFIP10 antibody, Zimp10 antibody, Zinc finger containing Miz1 PIAS like protein on chromosome 10 antibody, Zinc finger MIZ domain-containing protein 1 antibody, Zinc finger MIZ-type containing 1 antibody, Zmiz1 antibody, ZMIZ1_HUMAN antibody
Target Information: This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]